An ISO 9001:2008 & GMP certified company  | info@arlakbiotech.com  |  +91-9803023099, 7696263636  |  1800-121-6263 (Toll Free) 

NOIR DROPS


Categories: , .
Description

COMPOSITION: – AMOXYCILLIN & POTASSIUM CLAVULANATE ORAL SUSPENSION IP

PACKING: – 1X10ML

M.R.P: – 55

The medication is a combination of a type of penicillin antibiotics which has broad-spectrum for bacterial infections. It functions by stopping the growth of bacteria which results in treating the infection.

PHARMACOLOGY

PHARMACODYNAMICS:-

AMOXYCILLIN – The growth of bacterial cell wall is hindered as Amoxycillin interrupts with the cross-linkage between linear peptidoglycan polymer chains which form a major component of the cell walls of gram-positive as well as gram-negative bacteria.

CLAVULANIC ACID- It binds to amoxicillin to inhibit Beta-lactamase to inactivate amoxicillin from having an expanded spectrum of activity. It also inhibits the synthesis of the bacterial cell wall by binding to penicillin-binding proteins (PBP`S) which inhibits the formation of peptidoglycan ( a major component of bacteria`s cell wall).

PHARMACOKINETICS:-

Amoxicillin

Distribution: – Readily into most body tissues and fluids except the brain and spinal fluid.

Half-Life:- After oral admin: 1.3 hr (amoxicillin). About 50-70% of amoxicillin

Excretion: – Unchanged in urine during the 1st 6 hr after admin.

CLAVULANIC ACID

Clavulanic acid has a high affinity for and binds to certain β-lactamases that generally inactivate amoxicillin by hydrolyzing its β-lactam ring. Clavulanate potassium combines with amoxicillin which extends the antibacterial spectrum of amoxicillin to include many bacteria normally resistant to amoxicillin and other penicillins and cephalosporins.

INDICATIONS

AMOXICILLIN – CLAVULANATE POTASSIUM combination is treated bacterial infections caused by amoxicillin resistant bacteria.

 

Contact Us
close slider