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DESCRIPTION: Ferrous Ascorbate is obtained by reacting ascorbic acid and iron. It has excellent absorption as ascorbic acid enhances absorption of iron. Ascorbic acid reduces ferric iron to ferrous iron which remains soluble even at neutral pH. Folic Acid is a form of the water-soluble vitamin B9 and is a key factor in the synthesis of nucleic acid (DNA & RNA). It is vital for production of healthy red blood cells. MECHANISM OF ACTION: Ferrous Ascorbate when administered is converted to ferric form and immediately is reduced to the ferrous form into the stomach. This reduced ferrous form is then transferred to the duodenum where it is highly absorbed. Ferrous Ascorbate has the advantage of providing both ferrous ion and ascorbate in the same compound. There is no dissociation on entering GI Tract due to the stable chelate of iron with ascorbate. Folic Acid itself is biochemically inactive, is converted to tetrahydrofolic acid and methyltetrahydrofolate by dihydrofolate reductase in liver. These folic acid congeners are transported across cells by receptor-mediated endocytosis where they are needed to maintain numerous body functions. INDICATIONS: Indicated in the treatment of iron deficiency anemia, menorrhagia and folate deficiency anemia. Ferrous ascorbate reduces the risk of pre-eclampsia (pregnancy-induced hypertension) which generally occurs in severe or very severe anemia. Folic acid can reduce the risk of fetal neural tube defects. CONTRAINDICATIONS: Hypersensitivity to iron, should be avoided in patients who have bacterial infections. Contraindicated in patients who have hemosiderosis, hemochromatosis, and hemolyticanemia. DRUG INTERACTIONS: Iron compounds taken orally can impair the absorption of tetracycline antibiotics. Antacids given concomitantly with iron compounds decrease iron absorption. SIDE EFFECTS: Nausea, regurgitation, constipation, pyrosis (burning sensation in the chest), upset stomach may occur with the use of hematinics. Iron may cause your stools to turn black, an effect that is not harmful. PRECAUTIONS: Oral iron may aggravate existing peptic ulcer, regional enteritis and ulcerative colitis. DOSAGE: As directed by the physician. STORAGE: Store in a cool & dark place. Keep out of the reach of the children. PRESENTATION: 10x10 tablets in a cardboard carton
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