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Losrest-25


LEVOSULPIRIDE TABLET

PACKING :10X10

Description

Pharmacodynamics

Levosulpiride is a substituted benzamide, which exerts antidopaminergic (selective dopamine D2 receptors) activity on both central and peripheral levels. It is an atypical neuroleptic and a prokinetic agent.

Pharmacokinetics

Absorption: Oral bioavailability is about 30%; peak plasma concentrations after about 3 hr.
Excretion: Mainly via urine. Plasma half-life: 9.7 hr (oral); 4.3 hr (IV).

Levosulpiride Adverse Reactions / Levosulpiride Side Effects

Amenorrhoea, gynaecomastia, galactorrhoea, changes in libido.
Potentially Fatal: Neuroleptic malignant syndrome.

Special Precautions

May impair ability to drive or operate machinery. Pregnancy and lactation

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