PERIBEST

PERIBEST 150MG TAB


COMPOSITION:

TOLPERISONE 150MG

TOLPERISONE

Tolperisone is a centrally acting muscle relaxant launched for tht treatment of acute and chronic back pain and spasticity of neurological origin. Being a centrally acting muscle relaxant, tolperisone acts by blocking sodium channels and also known to possess significant effect on voltage- gated calcium channels

PHARMACOLOGY
PHARMACOKINETICS:

  • Absorption: Well absorbed from GI tract. Peak plasma concentration in 0.5-1 hr.
  • Bioavailability: 20%.
  • Metabolism: Extensively metabolized by liver and kidney
  • Excretion: Excreted mainly via urine as metabolites.

INDICATIONS:

  • Painful Muscle Spasms
  • Muscle Spasticities