URILIVER S MANUFACTURERS SUPPLIERS - THIRD PARTY CONTRACT MANUFACTURING
COMPOSITION:URSODEOXYCHOLIC ACID 300 MG + SILYMARIN 140MG
PACKING: 10*10 BLISTER
Ursodeoxycholic aciddiol is used to dissolve gallstones in patients who do not need to have their gallbladders removed or in those in whom surgery should be avoided because of other medical problems. However, Ursodeoxycholic aciddiol works only in those patients whose gallstones are made of cholesterol and works best when these stones are small and of the “floating” type. It is also used to help prevent gallstones in patients who are on rapid weight-loss programs. Ursodeoxycholic aciddiol is also used to treat primary biliary cirrhosis (PBC). PBC is an autoimmune disorder that causes a patient’s liver to have problems and not work properly. This medicine is available only with your doctor’s prescription. Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, Ursodeoxycholic aciddiol is used in certain patients with the following medical conditions: Chronic liver disease. Liver transplant (to help reduce the risk of rejection). Silymarin has metabolic and cell-regulating effects at concentrations found in clinical conditions, namely carrier-mediated regulation of cell membrane permeability, inhibition of the 5-lipoxygenase pathway, scavenging of reactive oxygen species (ROS) of the R-OH type and action on DNA-expression, for example, via suppression of nuclear factor (NF)-kappaB. Pooled data from case record studies involving 452 patients with Amanita phalloides poisoning show a highly significant difference in mortality in favour of silibinin [the main isomer contained in silymarin] (mortality 9.8% vs 18.3% with standard treatment; p < 0.01).