RIFAWAR – 400

RIFAWAR-400 Tablets contain Rifaximin 400 mg, a broad-spectrum, gut-selective antibiotic primarily used to treat intestinal and gastrointestinal infections. Rifaximin works locally in the intestine and is minimally absorbed into the bloodstream, making it highly effective with fewer systemic side effects.

RIFAWAR-400 is commonly prescribed for conditions such as traveller’s diarrhoea, irritable bowel syndrome with diarrhea (IBS-D), hepatic encephalopathy, and bacterial overgrowth in the gut. Its targeted action helps eliminate harmful bacteria while preserving beneficial gut flora, promoting faster recovery and improved digestive health.

Composition

Each tablet contains:

• Rifaximin – 400 mg
• Excipients q.s.

Working (Mechanism of Action)

Rifaximin works by inhibiting bacterial RNA synthesis by binding to the beta-subunit of bacterial DNA-dependent RNA polymerase. This action stops bacterial growth and replication in the gastrointestinal tract. Since Rifaximin remains largely within the gut, it effectively treats intestinal infections without causing significant systemic effects.

Uses / Indications

RIFAWAR-400 Tablets are used for the treatment of:

• Traveler’s diarrhea caused by bacterial infection
• Irritable bowel syndrome with diarrhea (IBS-D)
• Hepatic encephalopathy (to reduce ammonia-producing bacteria)
• Small intestinal bacterial overgrowth (SIBO)
• Acute infectious diarrhea
• Gut-related bacterial infections

Medicinal Benefits

• Targets the infection directly in the intestine
• Reduces the frequency of diarrhoea
• Improves gut health and digestive comfort
• Helps prevent recurrence of hepatic encephalopathy
• Minimal systemic absorption and fewer side effects
• Suitable for short- and long-term therapy under medical guidance

Dosage and Administration

Dosage should be taken as prescribed by the physician, some of the most commonly  r recommended dosage are : 

• Tablets should be swallowed whole with water
• Can be taken with or without food
• Do not skip doses or stop treatment prematurely

Side Effects

RIFAWAR-400 is generally well tolerated. Some patients may experience:

• Nausea
• Abdominal pain
• Flatulence
• Headache
• Dizziness

Most side effects are mild and temporary. Consult a doctor if symptoms persist or worsen.

Precautions

While using the medicine, there are certain precautions that must be followed to ensure a faster and safer recovery, such as 

• Not effective against viral or non-bacterial infections
• Use with caution in patients with severe liver disease
• Inform the doctor about any drug allergies
• Pregnant or breastfeeding women should consult a doctor before use
• Avoid self-medication and complete the prescribed course

Storage Instructions

• Store in a cool and dry place
• Protect from direct sunlight and moisture
• Keep out of reach of children
• Do not use after the expiry date

Frequently Asked Questions 

Q1. What is RIFAWAR-400 used for?
RIFAWAR-400 is used to treat gastrointestinal bacterial infections such as traveler’s diarrhea, IBS with diarrhea, hepatic encephalopathy, and gut bacterial overgrowth.

Q2. What is the active ingredient in RIFAWAR-400?
The active ingredient is Rifaximin 400 mg.

Q3. How does RIFAWAR-400 work?
Rifaximin works locally in the intestine by stopping the growth of infection-causing bacteria.

Q4. Can RIFAWAR-400 be used for viral diarrhea?
No, it is effective only against bacterial infections, not viral infections.

Q5. Can RIFAWAR-400 be taken with food?
Yes, it can be taken with or without food, as advised by the doctor.

Q6. Is RIFAWAR-400 safe for long-term use?
Long-term use should be done only under medical supervision.

Q7. What are the common side effects of RIFAWAR-400?
Common side effects may include nausea, abdominal pain, flatulence, headache, and dizziness.

Q8. Is RIFAWAR-400 safe during pregnancy?
Pregnant women should take it only if prescribed by a doctor.

Q9. Should the full course of RIFAWAR-400 be completed?
Yes, completing the full course helps prevent recurrence of infection.

Q10. How should RIFAWAR-400 be stored?
Store in a cool, dry place away from sunlight and moisture, and keep out of reach of children.