ESOMEPRAZOLE GASTRO RESISTANT 40 MG & LEVOSULPIRIDE 75 MG S.R CAPSULES

ESPENTRAL-LS is a fixed-dose combination designed for effective management of gastroesophageal reflux disease (GERD), dyspepsia, and associated motility disorders. It combines the potent acid-suppressing action of Esomeprazole with the prokinetic and antiemetic benefits of Levosulpiride.

Levosulpiride (75 mg SR) 

• • A substituted benzamide derivative with selective dopamine D₂ receptor antagonistic activity.

  • Enhances gastrointestinal motility and gastric emptying.

  • Exhibits antiemetic, prokinetic, and antidepressant properties.

Esomeprazole (40 mg) 

• • A proton pump inhibitor (PPI) that irreversibly inhibits H⁺/K⁺-ATPase in gastric parietal cells.

  • Provides sustained acid suppression, promotes mucosal healing, and relieves acid-related symptoms.

    Indications

    ESPENTRAL-LS is indicated for

    Gastroesophageal Reflux Disease (GERD)
    Non-ulcer dyspepsia
    Functional dyspepsia with delayed gastric emptying
    Nausea and vomiting associated with reflux disease
    Peptic ulcer disease (as adjunct therapy)
    Chronic gastritis with motility disorder