Description
MOXIFLOXACIN 0.5 5 + PREDNISOLONE 1 % EYE DROPS | NOIRMOX-P Eye Drops is a sterile topical ophthalmic formulation that contains a potent broad-spectrum antibiotic (Moxifloxacin) in combination with a powerful anti-inflammatory corticosteroid (Prednisolone). This indication provides therapeutic and prophylactic treatment for eye infections with an inflammatory component, including infections with redness, swelling and bacterial growth. Moxifloxacin is a fourth-generation fluoroquinolone with excellent activity against a large number of gram-positive and gram-negative ocular pathogens. Prednisolone is an anti-inflammatory corticosteroid that reduces inflammation, pain, and tissue destruction resulting from a bacterial eye infection or surgery on the eye.
Indications for its use
MOXIFLOXACIN 0.5 5 + PREDNISOLONE 1 % EYE DROPS | NOIRMOX-P Eye Drops are indicated for conditions such as
- For treating Bacterial conjunctivitis
- For treating Post-operative inflammation and infection
- Blepharitis, such as eyelid inflammation
- In Anterior uveitis
- Corneal ulcers
- Ocular trauma or surgery-associated infection/inflammation
Mechanism of action
The combination of this eye drop offers synergistic action – antimicrobial coverage as well as inflammation control.
Moxifloxacin (0.5%):
- We know it inhibits bacterial DNA gyrase and topoisomerase IV, which are important DNA replication and repair enzymes for reproduction in both Gram-positive and Gram-negative bacteria.
- Putting pressure on mechanisms of bacterial replication results in a rapid bactericidal effect and leads to infection resolution.
Prednisolone (1%):
- We know prednisolone binds to glucocorticoid receptors and inhibits inflammatory mediators, including other prostaglandins and cytokines.
- Suppresses any specific immune response from the eye involved in inflammation (including pain).
The combination offered synergistic action – antimicrobial coverage as well as inflammation control.
Dosages and administration
The dosages must be decided by the doctor and must be taken as per the recommendation by the doctor.
- The commonly recommended dose is
- One drop in the affected eye 3-4 times daily.
- In case of the severity of the condition, the drop dosage can vary.
- Wash your hands before using and avoid contact with the eye.
- Normal period of using it is 7-14 days.,
Possible side effects
This medication shows some side effects which are adapted by the body by Sometimes it may be required to get a medical checkup. Some of the common side effects are:
- Mild burning or stinging sensation
- Blurred vision temporarily after instillation
- Dryness or irritation in the eye
- Increased intraocular pressure
- Secondary fungal infection
- Delayed wound healing
- Mild burning or stinging sensation
- Blurred vision temporarily after instillation
- Dryness or irritation in the eye
- Increased intraocular pressure (with prolonged use of corticosteroids)
- Secondary fungal infection
- Delayed wound healing
Precautions while using MOXIFLOXACIN 0.5 5 + PREDNISOLONE 1 % EYE DROPS
For an effective and efficient use of the medicine without any unwanted condition or side effects, there are certain precautions that need to be followed, such as :
- It is not recommended for long-term use.
- Patients with glaucoma or herpes simplex keratitis must be cautious while using the medication.
- Avoid the use of contact lenses while using the drops.
- Do not use if the drop solution changes the colour or shows any unusual activity.
Storage Advice
- Store it in a cool, dry place away from direct sunlight
- Keep the container tightly closed.
- Keep away from sunlight.
