Description
Cefuroxime 500 Mg and Clavulanic Acid 125mg- This combination is composed of two medication formulations, Cefuroxime and Clavulanic Acid. This dual-action medication formulation helps in combating the bacterial infection caused by pathogenic bacteria. Cefuroxime, a second-generation cephalosporin antibiotic, works by inhibiting cell-wall formation in bacteria.
Hence, ultimately leads to the death of the bacteria. Whereas Clavulanic Acid, on the other hand, is a beta-lactamase inhibitor, it enhances the efficacy of cefuroxime. Thereby, making this combination effective against bacteria. This dual action makes it a reliable choice for both common and resistant bacterial infections. It is used for infections of the respiratory tract, urinary tract, skin and soft tissues, sinuses, ears, and more.
Arlak Biotec is a leading manufacturer and supplier of Cefuroxime and Clavulanic Acid Tablets, sold under the brand name RYFAX-CV.
Mechanism of Action: Cefuroxime and Clavulanic Acid Tablets
The working mechanism of Cefuroxime and Clavulanic Acid Tablets has been discussed as follows:
Cefuroxime– It inhibits the synthesis of the bacterial cell wall by binding to penicillin-binding proteins, blocking the final stages of peptidoglycan cross-linking. This results in the bacteria weakening and eventually rupturing, ultimately leading to their death.
Clavulanic Acid– It is a beta-lactamase inhibitor, though not a strong antibiotic on its own. It works by irreversibly binding to beta-lactamase enzymes produced by resistant bacteria. Hence, protecting cefuroxime from enzymatic degradation and enhancing its antibacterial effect.
Benefits and Uses of Cefuroxime and Clavulanic Acid Tablets
The Benefits and Uses of Cefuroxime and Clavulanic Acid Tablets are discussed as follows:
- Cefuroxime and Clavulanic Acid provide broad-spectrum activity against many Gram-positive and Gram-negative bacteria.
- It helps treat a variety of bacterial infections such as bronchitis, pneumonia, sinusitis, urinary tract infections, and skin and soft tissue infections.
- This combination is effective against conditions such as throat infections, otitis media (ear infections), sinusitis, gonorrhea, Lyme disease, and septicaemia.
Side Effects of Cefuroxime and Clavulanic Acid Tablets
Cefuroxime and Clavulanic Acid Tablets may cause some possible side effects. Usually, this medication is generally well-tolerated. These side effects disappear as the body adjusts to the doses. A list of Side Effects has been mentioned as follows:
- Diarrhoea
- Nausea
- Vomiting
- Abdominal pain
Safety Measures and Precautions
Disclose your previous or recent health issues to your healthcare provider. Consult your healthcare provider in case you feel discomfort. A list of safety measures and precautions is mentioned as follows:
- Inform your healthcare provider if you are allergic to cephalosporins or penicillin-like antibiotics.
- This combination is not prescribed for individuals who have kidney or liver impairment.
- Avoid using this antibiotic for viral infections such as the common cold or flu.
- Always complete the full prescribed course, even if symptoms improve early.
- Pregnant or breastfeeding patients should consult their doctor before use.
Storage Instructions for Cefuroxime and Clavulanic Acid Tablets
Follow the instructions mentioned as follows:
- Store the tablets at room temperature (below 25 °C) in a cool, dry place.
- Store the medication in a cool, dry place, away from direct sunlight and moisture.
- Store the medication in its original packaging.
- Always keep these medicines out of reach of children and pets.
- Do not use after the expiration date.
Frequently Asked Questions (FAQs)
Q1. What are common side effects?
Common side effects include nausea, diarrhea, stomach discomfort, and skin rashes. Contact your doctor if symptoms persist or worsen significantly.
Q2. Can pregnant or breastfeeding women take this medication?
Consult your doctor before use during pregnancy or breastfeeding. The doctor will assess the benefits versus the potential risks for you and your baby.
Q3. How long should I continue the treatment?
Complete the full prescribed course, typically 5-10 days, even if symptoms improve earlier. Stopping early may cause infection recurrence or resistance.
Q4. What is the recommended dosage?
Dosage varies by infection severity and patient condition. Typically, one tablet twice daily, but always follow your doctor’s specific prescription instructions.
Q5. Can I take this medication on an empty stomach?
It’s best taken with food to reduce stomach upset and improve absorption. Follow your healthcare provider’s guidance regarding timing.
Q6. What are common side effects?
Common side effects include nausea, diarrhea, stomach discomfort, and skin rashes. Contact your doctor if symptoms persist or worsen significantly.





