Cefixime and Sulbactam Tablets

Zefax-SB Tablets are a broad-spectrum antibiotic combination used for the effective treatment of various bacterial infections. This formulation combines Cefixime, a third-generation cephalosporin antibiotic, with Sulbactam, a beta-lactamase inhibitor. The addition of Sulbactam enhances the antibacterial activity of Cefixime by protecting it from bacterial resistance mechanisms.

Zefax-SB is widely prescribed in clinical practice for infections of the respiratory tract, urinary tract, ear, nose, throat, skin, and soft tissues. It is particularly useful in infections caused by resistant bacteria where single-antibiotic therapy may not be sufficient.

Composition

Each tablet contains:

• Cefixime
• Sulbactam
• Excipients q.s.

Working (Mechanism of Action)

• Cefixime works by inhibiting bacterial cell wall synthesis, leading to the destruction and death of bacteria.
• Sulbactam inhibits beta-lactamase enzyms produced by resistant bacteria, preventing them from inactivating Cefixime.

Together, this dual mechanism ensures enhanced antibacterial efficacy and broader coverage against resistant strains.

Uses / Indications

Zefax-SB Tablets are indicated for the treatment of:

• Respiratory tract infections
• Urinary tract infections (UTIs)
• Ear, nose, and throat (ENT) infections
• Skin and soft tissue infections
• Bacterial fever
• Community-acquired infections

Dosage and Administration

Dosage should be taken strictly as prescribed by the physician. Some of the recommended precautions are : 

• Tablets should be swallowed whole with water
• Can be taken with or without food
• Complete the full course of therapy even if symptoms improve
• Do not self-medicate or discontinue early

Side Effects

Zefax-SB is generally well tolerated. Some mild side effects may include:

• Nausea
• Diarrhea
• Stomach discomfort
• Headache
• Skin rash

If side effects persist or severe allergic reactions occur, seek medical advice immediately.

Precautions

While using the medicine, there are certain precautions that must be followed to ensure a faster and safer recovery, such as 

• Not effective against viral infections
• Use with caution in patients with kidney impairment
• Inform the doctor about any history of antibiotic allergy
• Pregnant or breastfeeding women should consult a doctor before use
• Avoid unnecessary or prolonged use to prevent resistance

Storage Instructions

• Store in a cool and dry place
• Protect from direct sunlight and moisture
• Keep out of reach of children
• Do not use after the expiry date

Frequently Asked Questions 

Q1. What are Zefax-SB Tablets used for?
Zefax-SB Tablets are used to treat bacterial infections of the respiratory tract, urinary tract, ENT, skin, and soft tissues.

Q2. What are the active ingredients in Zefax-SB Tablets?
They contain Cefixime and Sulbactam.

Q3. How do Zefax-SB Tablets work?
Cefixime kills bacteria, while Sulbactam prevents bacterial resistance, improving effectiveness.

Q4. Can Zefax-SB Tablets be used for viral infections?
No, they are effective only against bacterial infections.

Q5. How should Zefax-SB Tablets be taken?
They should be taken exactly as prescribed by the physician, with or without food.

Q6. Is it important to complete the full antibiotic course?
Yes, completing the full course prevents antibiotic resistance and relapse.

Q7. What are the common side effects of Zefax-SB Tablets?
Common side effects include nausea, diarrhea, stomach discomfort, headache, and mild skin rash.

Q8. Can Zefax-SB Tablets be taken during pregnancy?
They should be used during pregnancy only if prescribed by a doctor.

Q9. Who should use Zefax-SB Tablets with caution?
Patients with kidney problems or a history of antibiotic allergy should use them with caution.

Q10. How should Zefax-SB Tablets be stored?
Store in a cool, dry place away from sunlight and moisture, and keep out of reach of children.