Description
COMPOSITION:
SIMETHICONE & MAGALDRATE
PHARMACOLOGY
1.MAGALDRATE
a.)Pharmacodynamics: – This neutralizes the gastric acid and increases the gastric pH. This reduces the direct acid irritant effect. It also enhances mucosal barrier integrity and improves gastroesophageal sphincter tone.
b.)Pharmacokinetics: –
- Absorption: – Moderately absorbed after oral administration.
- Distribution- It is distributed through locally.
- Excretion- Excreted through feces and a small amount through breast milk.
2.SIMETHICONE
a.)Pharmacodynamics: – This anti-gas (anti-flatulence) medication acts in the stomach and intestines to change the surface tension of gas bubbles, enabling smaller bubbles to join together into bigger bubbles. It results elimination of gas more easily by belching or passing flatus.
b.)Pharmacokinetics: –
Excretion- Excreted through feces.
INDICATIONS:
- Condition in which Stomach Acid is Pushed Into the Esophagus Medications
- Stomach Ulcer Medications
- Ulcer of the Duodenum Medications
- Ulcer from Stomach Acid Medications
- Conditions of Excess Stomach Acid Secretion Medications
