Description
MEDICATION USED FOR
It may be used to treat conditions caused by low calcium levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain muscle disease (latent tetany).
CALCITRIOL:
- Well tolerated, safe and significantly reduces the rate of new vertebral fractures in women with Postmenopausal Osteoporosis’
- Controls parathyroid gland growth and suppresses the synthesis and secretion of parathyroid hormone thereby used in the treatment of secondary hyperparathyroidism
CALCIUM CITRATE MALEATE:
- Exhibit PH independent absorption
- Is less amenable to the formation of calcium phytate complex than any other calcium salt
ZINC:
- Beneficial role and exhibits positive association in increasing BMD (Bone Mineral Density)
INDICATIONS
Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. It is vital in cell signaling, muscular contractions, bone health, and signalling cascades.
CALCITRIOL:
- Regulates calcium levels by increasing the absorption of calcium & phosphate
- Maintains strength of bones, teeth and a healthy immune system
- common medication in the treatment of hypocalcemia and osteoporosis
- Treats vitamin D deficiency, low calcium is post menopausal women
CALCIUM CITRATE MALEATE:
- Prevents bone & joint weakening with weight regulation effects
- Assist in maintainging all cell connective tissues in the body
- Essential for normal bone formation & is involved in the biochemical activities of Vit D
ZINC:
- Signiflcant role in collagen synthesis & cell proliferation during wound healing process
MECHANISM OF ACTION
Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. More than 500 human proteins are known to bind or transport calcium. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the free, ionized form or bound to blood proteins such as serum albumin. Parathyroid hormone (secreted from the parathyroid gland) regulates the resorption of Ca2+ from bone. Calcitonin stimulates incorporation of calcium in bone, although this process is largely independent of calcitonin.
