MEDICATION USED FOR
ALBENDAZOLE & IVERMECTIN ( AVER-PLUS)tab is in a class of medication called anthelmintics. Albendazole & Ivermectin (AVER-PLUS) tab is used to treat certain worms and parasitic infections.
ALBENDAZOLE:- Albendazole is used to prevent newly hatched insect larvae (worms) from growing or multiplying in your body.Albendazole is used to treat neurocysticercosis (infection caused by the pork tapeworm in the muscle brain swelling and vision problems. Albendazole is also used along with surgery to treat cystic hydrated diseases (infection caused the dog tapeworm in the liver, lung, and lining of the abdomen that may damage these organs.
IVERMECTIN:-Ivermectin is curing parasitic infection help to improve your quality of life. In people with weakened defense (immune system)curing roundworms, infections can reduce the risk of developing severe or life-threatening infections. Itis also used to treat lice and scabies.
For the treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia solium and for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus.
For the treatment of intestinal (i.e., nondisseminated) strongyloidiasis due to the nematode parasite Strongyloides stercoralis. Also for the treatment of onchocerciasis (river blindness) due to the nematode parasite Onchocerca volvulus. Can be used to treat scabies caused by Sarcoptes scabiei.
MECHANISM OF ACTION
AVER PLUS lbendazole works by killing the worms. Albendazole works by immobilizing and killing the worms and prevent the newly hatched larvae from multiplying inside the body. Albendazole’s actions include interfering with microtubule synthesis and inhibiting glucose uptake by helminthic cells. Albendazole by its inhibitory effect on tubulin polymerization which results in the loss of cytoplasmic microtubules . AVER PLUSIvermectin binds with high affinity to glutamate-gated chloride channels which occurs in invertebrate nerve and muscle cells, causing an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cells.