LOSREST INJ MANUFACTURERS SUPPLIERS - THIRD PARTY CONTRACT MANUFACTURING
LOSREST INJ
LOSREST
COMPOSITION:LEVOSULPIRIDE 12.5mg
PACKING:10X2ML AMP
Description
Pharmacodynamics
Levosulpiride is a substituted benzamide, which exerts antidopaminergic (selective dopamine D2 receptors) activity on both central and peripheral levels. It is an atypical neuroleptic and a prokinetic agent.
Pharmacokinetics
Absorption: Oral bioavailability is about 30%; peak plasma concentrations after about 3 hr.
Excretion: Mainly via urine. Plasma half-life: 9.7 hr (oral); 4.3 hr (IV).
Levosulpiride Adverse Reactions / Levosulpiride Side Effects
Amenorrhoea, gynaecomastia, galactorrhoea, changes in libido.
Potentially Fatal: Neuroleptic malignant syndrome.
Special Precautions
May impair ability to drive or operate machinery. Pregnancy and lactation
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